{"id":48,"date":"2019-05-12T18:47:41","date_gmt":"2019-05-12T16:47:41","guid":{"rendered":"https:\/\/www.bbemg.uliege.be\/?page_id=48"},"modified":"2023-12-07T10:30:53","modified_gmt":"2023-12-07T09:30:53","slug":"meta-analyse-de-la-leucemie-infantile","status":"publish","type":"page","link":"https:\/\/www.bbemg.uliege.be\/fr\/meta-analyse-de-la-leucemie-infantile\/","title":{"rendered":"M\u00e9ta-analyse de la leuc\u00e9mie infantile"},"content":{"rendered":"[vc_row type=\u00a0\u00bbin_container\u00a0\u00bb full_screen_row_position=\u00a0\u00bbmiddle\u00a0\u00bb scene_position=\u00a0\u00bbcenter\u00a0\u00bb text_color=\u00a0\u00bbdark\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb overlay_strength=\u00a0\u00bb0.3″ shape_divider_position=\u00a0\u00bbbottom\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb][vc_column column_padding=\u00a0\u00bbno-extra-padding\u00a0\u00bb column_padding_position=\u00a0\u00bball\u00a0\u00bb background_color_opacity=\u00a0\u00bb1″ background_hover_color_opacity=\u00a0\u00bb1″ column_link_target=\u00a0\u00bb_self\u00a0\u00bb column_shadow=\u00a0\u00bbnone\u00a0\u00bb column_border_radius=\u00a0\u00bbnone\u00a0\u00bb width=\u00a0\u00bb1\/1″ tablet_width_inherit=\u00a0\u00bbdefault\u00a0\u00bb tablet_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb phone_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb column_border_width=\u00a0\u00bbnone\u00a0\u00bb column_border_style=\u00a0\u00bbsolid\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb][heading]\n

M\u00e9ta-analyse de la leuc\u00e9mie infantile<\/h1>\n[\/heading][\/vc_column][\/vc_row][vc_row type=\u00a0\u00bbin_container\u00a0\u00bb full_screen_row_position=\u00a0\u00bbmiddle\u00a0\u00bb scene_position=\u00a0\u00bbcenter\u00a0\u00bb text_color=\u00a0\u00bbdark\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb overlay_strength=\u00a0\u00bb0.3″ shape_divider_position=\u00a0\u00bbbottom\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb][vc_column column_padding=\u00a0\u00bbno-extra-padding\u00a0\u00bb column_padding_position=\u00a0\u00bball\u00a0\u00bb background_color_opacity=\u00a0\u00bb1″ background_hover_color_opacity=\u00a0\u00bb1″ column_link_target=\u00a0\u00bb_self\u00a0\u00bb column_shadow=\u00a0\u00bbnone\u00a0\u00bb column_border_radius=\u00a0\u00bbnone\u00a0\u00bb width=\u00a0\u00bb1\/1″ tablet_width_inherit=\u00a0\u00bbdefault\u00a0\u00bb tablet_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb phone_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb column_border_width=\u00a0\u00bbnone\u00a0\u00bb column_border_style=\u00a0\u00bbsolid\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb][vc_custom_heading text=\u00a0\u00bbObjectifs\u00a0\u00bb font_container=\u00a0\u00bbtag:h2|text_align:left|color:%2349b0e5″ use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb][vc_column_text]Dans le cadre du projet du BBEMG, l’Unit\u00e9 de Recherche en Sant\u00e9 publique, \u00c9pid\u00e9miologie et \u00c9conomie de la Sant\u00e9 \u00e9tudie l\u2019impact des champs \u00e9lectromagn\u00e9tiques sur la sant\u00e9 en se basant sur des m\u00e9ta-analyses. Plusieurs \u00e9tudes ont examin\u00e9 la relation qui existe entre la pr\u00e9sence de champs \u00e9lectromagn\u00e9tiques et l\u2019apparition de la leuc\u00e9mie chez l\u2019enfant (Kabuto et al., 2006; Linet et al., 1997; Michaelis et al., 1997). Cependant, de nombreux r\u00e9sultats contradictoires ont \u00e9t\u00e9 obtenus dans ce domaine de recherche. Certaines \u00e9tudes ont montr\u00e9 que la leuc\u00e9mie infantile pourrait \u00eatre associ\u00e9e avec les champs \u00e9lectromagn\u00e9tiques de fr\u00e9quences extr\u00eamement basses (ELF) mais d\u2019autres recherches n\u2019ont pas trouv\u00e9 de relation entre ces variables. Pour cette raison, il est important de mener des m\u00e9ta-analyses de qualit\u00e9 pour d\u00e9terminer si l\u2019exposition aux champs \u00e9lectromagn\u00e9tiques peut r\u00e9ellement augmenter le risque d\u2019avoir la leuc\u00e9mie chez l\u2019enfant.<\/p>\n

La m\u00e9ta-analyse est une analyse statistique qui combine les r\u00e9sultats de plusieurs \u00e9tudes diff\u00e9rentes. Cette analyse fournit une synth\u00e8se des diff\u00e9rents r\u00e9sultats qui traitent d\u2019une m\u00eame question. Les m\u00e9ta-analyses sont souvent consid\u00e9r\u00e9es comme le niveau le plus \u00e9lev\u00e9 de preuve scientifique et de v\u00e9racit\u00e9 par la communaut\u00e9 scientifique (Borenstein et al. 2009). Malheureusement, la m\u00e9ta-recherche (l\u2019\u00e9tude scientifique du fonctionnement de la science) a bien d\u00e9montr\u00e9 que dans bon nombre de domaines des sciences de la sant\u00e9, la qualit\u00e9 proc\u00e9durale et statistique des m\u00e9ta-analyses disponibles pose souvent probl\u00e8me, ce qui invalide fr\u00e9quemment leurs conclusions (Ioannids 2015; Ioannidis et al. 2016). Pour cette raison, il est essentiel de mener des m\u00e9ta-analyses qui se basent sur les proc\u00e9dures statistiques ad\u00e9quates et des revues syst\u00e9matiques de la litt\u00e9rature qui prennent en compte les recommandations de qualit\u00e9 m\u00e9thodologique internationales PRISMA (Beaudart et al., 2016; Rabenda et al., 2017\u00a0; voir le site de PRISMA dans les R\u00e9f\u00e9rences). Dans notre unit\u00e9, nous conduisons une revue syst\u00e9matique de la litt\u00e9rature et une m\u00e9ta-analyse pour clarifier le lien qui existe entre l\u2019exposition aux champs \u00e9lectromagn\u00e9tiques ELF et l\u2019apparition de la leuc\u00e9mie infantile.<\/p>\n

La publication d\u00e9crivant les r\u00e9sultats de cette m\u00e9ta-analyse peut \u00eatre consult\u00e9e ici.<\/a>[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=\u00a0\u00bbin_container\u00a0\u00bb full_screen_row_position=\u00a0\u00bbmiddle\u00a0\u00bb scene_position=\u00a0\u00bbcenter\u00a0\u00bb text_color=\u00a0\u00bbdark\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb overlay_strength=\u00a0\u00bb0.3″ shape_divider_position=\u00a0\u00bbbottom\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb][vc_column column_padding=\u00a0\u00bbno-extra-padding\u00a0\u00bb column_padding_position=\u00a0\u00bball\u00a0\u00bb background_color_opacity=\u00a0\u00bb1″ background_hover_color_opacity=\u00a0\u00bb1″ column_link_target=\u00a0\u00bb_self\u00a0\u00bb column_shadow=\u00a0\u00bbnone\u00a0\u00bb column_border_radius=\u00a0\u00bbnone\u00a0\u00bb width=\u00a0\u00bb1\/1″ tablet_width_inherit=\u00a0\u00bbdefault\u00a0\u00bb tablet_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb phone_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb column_border_width=\u00a0\u00bbnone\u00a0\u00bb column_border_style=\u00a0\u00bbsolid\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb][vc_custom_heading text=\u00a0\u00bbR\u00e9f\u00e9rences\u00a0\u00bb font_container=\u00a0\u00bbtag:h3|text_align:left|color:%233f3f3f\u00a0\u00bb use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb][vc_column_text]Beaudart, Charlotte ; Rabenda, V\u00e9ronique ; Bruy\u00e8re, Olivier (2016) Il n’est jamais trop tard pour apprendre \u00e0 (bien) lire … La revue syst\u00e9matique. Medi-Sphere 525: 35-38.<\/p>\n

Borenstein M, Hedges LV, Higgins JPT, Rothstein HR (2009) Introduction to meta-analysis. New York: Wiley & Sons.<\/p>\n

Kabuto M, Nitta H, Yamamoto S, Yamaguchi N, Akiba S, Honda Y, Hagihara J, Isaka K, Saito T, Ojima T, Nakamura Y, Mizoue T, Ito S, Eboshida A, Yamazaki S, Sokejima S, Kurokawa Y, Kubo O (2006) Childhood leukemia and magnetic fields in Japan: a case-control study of childhood leukemia and residential power-frequency magnetic fields in Japan. Int J Cancer 119: 643-50.<\/p>\n

Linet MS, Hatch EE, Kleinerman RA, Robison LL, Kaune WT, Friedman DR, Severson RK, Haines CM, Hartsock CT, Niwa S, Wacholder S, Tarone RE (1997) Residential exposure to magnetic fields and acute lymphoblastic leukemia in children. N Engl J Med 337: 1-7.<\/p>\n

Ioannidis JP (2016) The mass production of redundant, misleading and conflicting systematic reviews and meta-analyses. Milbank Quart 94: 485-514.<\/p>\n

Ioannidis JP, Fanelli D, Dunne DD, Goodman SN (2015) Meta-research: evaluation and improvement of research methods and practices. PLOS BIOL 13: e1002264.<\/p>\n

Michaelis J, Sch\u00fcz J, Meinert R, Menger M, Grigat JP, Kaatsch P, Kaletsch U, Miesner A, Stamm A, Brinkmann K, K\u00e4rner H (1997) Childhood leukemia and electromagnetic fields: results of a population-based case-control study in Germany. Cancer Causes Control 8: 167-74.<\/p>\n

PRISMA website:\u00a0http:\/\/www.bmj.com\/content\/339\/bmj.b2700<\/a><\/p>\n

Rabenda V, Beaudart C, Bruy\u00e8re, O (2017) Il n’est jamais trop tard pour apprendre \u00e0 (bien) lire … La M\u00e9ta-Analyse. Ortho-Rhumato 15: 27-32.[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=\u00a0\u00bbin_container\u00a0\u00bb full_screen_row_position=\u00a0\u00bbmiddle\u00a0\u00bb scene_position=\u00a0\u00bbcenter\u00a0\u00bb text_color=\u00a0\u00bbdark\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb overlay_strength=\u00a0\u00bb0.3″ shape_divider_position=\u00a0\u00bbbottom\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb][vc_column column_padding=\u00a0\u00bbno-extra-padding\u00a0\u00bb column_padding_position=\u00a0\u00bball\u00a0\u00bb background_color_opacity=\u00a0\u00bb1″ background_hover_color_opacity=\u00a0\u00bb1″ column_link_target=\u00a0\u00bb_self\u00a0\u00bb column_shadow=\u00a0\u00bbnone\u00a0\u00bb column_border_radius=\u00a0\u00bbnone\u00a0\u00bb width=\u00a0\u00bb1\/1″ tablet_width_inherit=\u00a0\u00bbdefault\u00a0\u00bb tablet_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb phone_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb column_border_width=\u00a0\u00bbnone\u00a0\u00bb column_border_style=\u00a0\u00bbsolid\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb][vc_custom_heading text=\u00a0\u00bbInformations compl\u00e9mentaires\u00a0\u00bb font_container=\u00a0\u00bbtag:h2|text_align:left|color:%2349b0e5″ use_theme_fonts=\u00a0\u00bbyes\u00a0\u00bb][vc_column_text]\n